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Old 10-04-2010, 09:57 AM   #2
Rich66
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Location: South East Wisconsin
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Re: 80% clinical response to tax+avastin+herceptin combo as 1st line mbc treatment --

So they continued the Herceptin/Avastin after the cycles of Taxotere? I wonder if survival would be improved if Herceptin or Herceptin/Avastin was continued past progression.


Not sure I'm tracking this:

Quote:
The regimen was generally well tolerated, including no increased risk of cardiotoxicity
Quote:
However, cardiotoxicity complicated treatment in almost 40% of the cases.
So...same as other treatments i.e. 40%?

I wonder if there is any data on Taxotere/Herceptin without Avastin.

"Data from correlational studies of circulating tumor cells and circulating endothelial cells will be reported at a later date"

That would be interesting.

I'd also be curious about the combo with Abraxane instead of Taxotere.
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