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Re: level of Her2...plays a role also
Hey, Rich, wasn't there a mushroom that helped to inhibit GRB7? Seems to me you posted something on this a while back.
Hayley, I love the new avatar! It appears from this article that in the future they will test for GRB7 to see if it is present and to what degree. It's presence, probably the amount of its presence, may fuel the Her-2 fire and therefore must be inhibited by a yet to be produced med given in conjunction with Herceptin. It sounds as though there is quite a long way to go on this, but this may answer the question of why some recur despite Herceptin or progress while on it.
Great post, Jean, thanks!
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Smile On!
Laurel
Dx'd w/multifocal DCIS/IDS 3/08
7mm invasive component
Partial mast. 5/08
Stage 1b, ER 80%, PR 90%, HER-2 6.9 on FISH
0/5 nodes
4 AC, 4 TH finished 9/08
Herceptin every 3 weeks. Finished 7/09
Tamoxifen 10/08. Switched to Femara 8/09
Bilat SPM w/reconstruction 10/08
Clinical Trial w/Clondronate 12/08
Stopped Clondronate--too hard on my gizzard!
Switched back to Tamoxifen due to tendon pain from Femara
15 Years NED
I think I just might hang around awhile....
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