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Chelee · 07-30-2010, 03:17 PM

Joan, I have decided to pass on this trial. I was really only interested in T-DM1 if I had to drive that far wkly. (2 hrs one way) I also found out there is no cross over to T-DM1 if I were to get the Tykerb/Xeloda arm and progress. I also don't like the idea that I will be off Herceptin if I get the Tykerb/Xeloda arm. (My CA27.29 dropped when I started back on Herceptin.)

Now I don't know what to do? I still have lots of questions and no answers? I was hoping when I was out at UCLA I could cover all my options but there just didn't seem to be enough time. It was mainly about the trial and what was involved in it. My onc is going to ask me what I want to do and I haven't a clue? Maybe Tykerb/Herceptin like Dr. Slamon mentioned to me at a prior appt...I just don't know? If anyone has any idea's I'd love to hear them...might help me brainstorm this a bit. CA27.29 was still in NED range...so low measurable disease so far.

(I've had so many distractions...one very ill dog and my MIL fell and broke her hip. Trying to take care of everyone & myself...when it rains it pours.)

Chelee

07-30-2010, 03:17 PM	#42
Chelee Senior Member Join Date: Feb 2006 Location: Southern, CA Posts: 2,511	Re: It's back... Joan, I have decided to pass on this trial. I was really only interested in T-DM1 if I had to drive that far wkly. (2 hrs one way) I also found out there is no cross over to T-DM1 if I were to get the Tykerb/Xeloda arm and progress. I also don't like the idea that I will be off Herceptin if I get the Tykerb/Xeloda arm. (My CA27.29 dropped when I started back on Herceptin.) Now I don't know what to do? I still have lots of questions and no answers? I was hoping when I was out at UCLA I could cover all my options but there just didn't seem to be enough time. It was mainly about the trial and what was involved in it. My onc is going to ask me what I want to do and I haven't a clue? Maybe Tykerb/Herceptin like Dr. Slamon mentioned to me at a prior appt...I just don't know? If anyone has any idea's I'd love to hear them...might help me brainstorm this a bit. CA27.29 was still in NED range...so low measurable disease so far. (I've had so many distractions...one very ill dog and my MIL fell and broke her hip. Trying to take care of everyone & myself...when it rains it pours.) Chelee __________________ DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes. Rt. MRM on 1-3-06 -- No Rads due to compromised lungs. Chemo started 2-7-06 -- TCH - - Finished 6-12-06 Finished yr of wkly herceptin 3-19-07 3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07 9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV. 9-28-09 Loading dose of Herceptin & started Zometa 9-29-09 Power Port Placement 10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head. 11-19-09 RT. Femur surgery - Rod placed 12-7-09 Navelbine added to Herceptin/Zometa. 3-23-10 Ten days of rads to RT femur. Completed. 4-05-10 Quit Navelbine--Herceptin/Zometa alone. 5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy. Results to FISH was unsuccessful--this happens less then 2% of the time. 7-7-10 Recurrence to RT axilla again. Back to UCLA for options.