HER2 Support Group Forums - View Single Post - Recurrence for ER+/PR-/HER-2+ tumors

Jackie07 · 06-24-2010, 10:24 PM

Marcia,

I'm also ER+ PR-. Even though the ER amount was very small (5%?), a doctor I consulted (my 2nd Sister-in-law's oncologist in Taiwan) had told me that either 5 years of Tamoxifen or 2 years of Tamoxifen + 3 years of Arimedix (or other aromatease inhibitor) is recommended.

One does need to watch for the side effect of osteoporosis as is evidenced by the cervical vertebrae degeneration I'm currently experiencing.

I think the recurrence rate has more to do with the types of surgery (lumpectomy vs mastectomy) than any other factor. My surgeon has quoted statistics by saying that lumpectomy + radiation = mastectomy. I personally never bought that...

In my case, there was tumor left-over from the lumpectomy and the recurrence was overlooked for 4 years. So I don't quite buy the 'peak' theory. I think it has more to do with how long it takes the doctors to realize their mistakes. (In my case, they never did find it. I had to be the one persuing it.)

In your case, I think because you'd had neo-adjuvant treatment and mastectomy plus further chemo/Herceptin you should have a good chance not to have any recurrence in the near future.

Just be vigilent, you will be fine.

06-24-2010, 10:24 PM	#4
Jackie07 Senior Member Join Date: Jan 2008 Location: "Love never fails." Posts: 5,809	Re: Recurrence for ER+/PR-/HER-2+ tumors Marcia, I'm also ER+ PR-. Even though the ER amount was very small (5%?), a doctor I consulted (my 2nd Sister-in-law's oncologist in Taiwan) had told me that either 5 years of Tamoxifen or 2 years of Tamoxifen + 3 years of Arimedix (or other aromatease inhibitor) is recommended. One does need to watch for the side effect of osteoporosis as is evidenced by the cervical vertebrae degeneration I'm currently experiencing. I think the recurrence rate has more to do with the types of surgery (lumpectomy vs mastectomy) than any other factor. My surgeon has quoted statistics by saying that lumpectomy + radiation = mastectomy. I personally never bought that... In my case, there was tumor left-over from the lumpectomy and the recurrence was overlooked for 4 years. So I don't quite buy the 'peak' theory. I think it has more to do with how long it takes the doctors to realize their mistakes. (In my case, they never did find it. I had to be the one persuing it.) In your case, I think because you'd had neo-adjuvant treatment and mastectomy plus further chemo/Herceptin you should have a good chance not to have any recurrence in the near future. Just be vigilent, you will be fine. __________________ Jackie07 http://www.kevinmd.com/blog/2011/06/doctors-letter-patient-newly-diagnosed-cancer.html http://www.asco.org/ASCOv2/MultiMedi...=114&trackID=2 NICU 4.4 LB Erythema Nodosum 85 Life-long Central Neurocytoma 4x5x6.5 cm 23 hrs 62090 semi-coma 10 d PT OT ST 30 d 3 Infertility tmts 99 > 3 u. fibroids > Pills CN 3 GKRS 52301 IDC 1.2 cm Her2 +++ ER 5% R. Lmptmy SLNB+1 71703 6 FEC 33 R Tamoxifen Recc IIB 2.5 cm Bi-L Mast 61407 2/9 nds PET 6 TCH Cellulitis - Lymphedema - compression sleeve & glove H w x 4 MUGA 51 D, J 49 M Diastasis recti Tamoxifen B. scan Irrtbl bowel 1'09 Colonoscopy 313 BRCA1 V1247I hptc hemangioma Vertigo GI - > yogurt hysterectomy/oophorectomy 011410 Exemestane 25 mg tab 102912 ~ 101016 stopped due to r. hip/l.thigh pain after long walk DEXA 1/13 1-2016 lesions in liver largest 9mm & 1.3 cm onco. says not cancer. 3-11 Appendectomy - visually O.K., a lot of puss. Final path result - not cancer. Start Vitamin D3 and Calcium supplement （600mg x2) 10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016 7-23-2018 9 mm groundglass nodule within the right lower lobe with indolent behavior. Due to possible adenocarcinoma, Recommend annual surveilence. 7-10-2019 CT to check lung nodule. 1-10-2020 8mm stable nodule on R Lung, two 6mm new ones on L Lung, a possible lymph node involvement in inter fissule. "I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY." Irene from Tampa Advocacy is a passion .. not a pastime - Joe Last edited by Jackie07; 06-25-2010 at 12:39 AM..