[jellybean]

Hi All,

I have inflammatory breast cancer that is Her2 positive. I was Stage IV from the outset, with widespread metastatic disease. After three cycles of TCH I was NED, and I continued with TCH for a total of 6 cycles, and then had a mastectomy and radiation. I have been NED for three years. In August it will be three years on Herceptin and hormonal treatment alone. I was recently diagnosed with what probably is a very small new primary in my "good" breast, although it is conceivable it is a metastasis. It has the identical pathology to the original tumor in my other breast (Her2 positive, ER positive, PR negative). I will be having a mastectomy at the end of June. I am thinking of having a second opinion on the appropriate change (if any) in systemic treatment after I get my pathology back from the surgery. I live in San Francisco, and I am treated by a top onc at UCSF. I am sure whatever advice she gives me will be excellent. I just would feel more comfortable if I had a second opinion.

Would Dr. Slamon be a good choice for a second opinion? I have a lot of questions, and I am looking for someone that will take the time to respond to them. Of course, I know he has a lot of insight into Her2 positive disease since he was behind the development of Herceptin. I also suspect that as a researcher he would be curious about whether the tumor is a new primary or a metastasis and whether it matters in terms of deciding on the therapy.

If you feel more comfortable pming me, that's fine too. If you have other ideas on a second opinion doctor, that would be helpful too.

Thanks much,

JB