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Lani · 05-15-2010, 03:38 AM

Nance there is a lot new in triple negative bc. Some are considered basal subgroup and others not. Those that are not have a better prognosis than her2+ bc usually. There are markers to look for to see which type of triple negative you have including CK5, EGFR, etc.

They are having much better results than in the past with cisplatin,PARP inhibitors, dasatinib and potentially even EGFR inhibitors(EGFR is also known as her1!)

Again many patients who are triple negative have much better prognoses than her2+ patients AND they get to find out earlier if they have beaten the odds, as they tend to have a single "hump" of recurrence which does not go on for years and years (vs. triple positives)

There is lots of information out there, just different information and usually one third to half the sessions at bc conferences I attend are on triple negative.

Good luck!

05-15-2010, 03:38 AM	#10
Lani Senior Member Join Date: Mar 2006 Posts: 4,783	Re: Triple Negative Nance there is a lot new in triple negative bc. Some are considered basal subgroup and others not. Those that are not have a better prognosis than her2+ bc usually. There are markers to look for to see which type of triple negative you have including CK5, EGFR, etc. They are having much better results than in the past with cisplatin,PARP inhibitors, dasatinib and potentially even EGFR inhibitors(EGFR is also known as her1!) Again many patients who are triple negative have much better prognoses than her2+ patients AND they get to find out earlier if they have beaten the odds, as they tend to have a single "hump" of recurrence which does not go on for years and years (vs. triple positives) There is lots of information out there, just different information and usually one third to half the sessions at bc conferences I attend are on triple negative. Good luck!