Quote:
Specific proteins are present on the surface of tumor cells, such as PSMA on prostate cancer cells. Using nucleic acid technology, the researchers developed a small interfering RNA (siRNA) which inhibits the nonsense mediated mRNA decay process
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Despite the misleading acronym (Prostate specific membrane antigen), this protein is found in other cancers, including breast. A drug in phase 1 trial,
G202, works with this.
Maybe that could help speed the development of this towards BC.
I do like the concept of inhibiting "nonsense".