[Rich66]

Even more disconcerting from an efficacy and reimbursement standpoint is the emerging concept(recently posted here) that breast cancer stem cells may be vulnerable to Her2 therapies regardless of test results. How do you get reimbursed for Herceptin, as suggested, for multiple years with a FISH negative result? You don't.
But..you can go after this pathway, along with EGFR, to some degree with Capsaicin and green tea.