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Barbara2 · 03-11-2010, 10:59 AM

Risk of Recurrent Disease in HER2-Positive Patients

I had posted this in the "Articles of Interest" section, but thought I would move it over here, too. The article contained some info I had not seen before and thought it might generate some discussion amoungst the Her2+ ER+ people.

Daniel F. Hayes, MD:
What I find interesting about this study is that with ER-positive cancer there is an ongoing risk of recurrence for a long period of time. It looks as though there is a secondary spike between 8 and 12 years. Dr. Goss did not necessarily agree with that, but there have been some reports of this, whereas in ER-negative patients, the tumor recurs within the first 5-7 years or it does not recur.

Here is the entire article:http://www.clinicaloptions.com/Oncol...Page%2012.aspx

Hopeful also pasted the article there.

03-11-2010, 10:59 AM	#1
Barbara2 Senior Member Join Date: Sep 2005 Location: South Dakota. Posts: 621	Of interest to Her2+ ER+ Risk of Recurrent Disease in HER2-Positive Patients I had posted this in the "Articles of Interest" section, but thought I would move it over here, too. The article contained some info I had not seen before and thought it might generate some discussion amoungst the Her2+ ER+ people. Daniel F. Hayes, MD: What I find interesting about this study is that with ER-positive cancer there is an ongoing risk of recurrence for a long period of time. It looks as though there is a secondary spike between 8 and 12 years. Dr. Goss did not necessarily agree with that, but there have been some reports of this, whereas in ER-negative patients, the tumor recurs within the first 5-7 years or it does not recur. Here is the entire article:http://www.clinicaloptions.com/Oncol...Page%2012.aspx Hopeful also pasted the article there. __________________ Blessings and Peace, Barbara DX Oct 02 @ age 52 Stage 2B Grade 3 Mastectomy "at least" 4.5 cm IDC 1+node ER+61% /PR- Assiciated Intraductual component with Comedo Necrosis Her2+ FISH8.6 IHC 2+ 5 1/2 CEF Arimidex Celebrex 400mg daily for 13 months Prophylactic mastectomy Estradiol #: 13 PTEN positive, "late" Herceptin (26 months after chemo) Oct 05: Actonel for osteopenia from Arimidex. May 08: Replaced Actonel with Zometa . Taking every 6 months. Accepting the gift of life, I give thanks for it and live it in fullness.