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Jean · 03-07-2010, 10:17 PM

Hi Diane,
According to this article the researchers discovered that the protein MKL3 which causes cell death there maybe interference when taking drugs to halt estrogen.

The researchers are attempting to prove this so that can come with a drug to work with the anti hormone drugs.

It is a catch 21 right now, as someone like myself who had a high estrogen reading 90% really does not have much of a choice deciding to take an AI. If I were 1% that would change decisions.

Our bodies and how they manufacture certain proteins and enzymes are still a mystery. This protein MKL3 prove to be very vital.

Best Wishes,
Jean

03-07-2010, 10:17 PM	#7
Jean Senior Member Join Date: Oct 2005 Location: New Jersey Posts: 3,154	Re: For Laurel and others who have been Hi Diane, According to this article the researchers discovered that the protein MKL3 which causes cell death there maybe interference when taking drugs to halt estrogen. The researchers are attempting to prove this so that can come with a drug to work with the anti hormone drugs. It is a catch 21 right now, as someone like myself who had a high estrogen reading 90% really does not have much of a choice deciding to take an AI. If I were 1% that would change decisions. Our bodies and how they manufacture certain proteins and enzymes are still a mystery. This protein MKL3 prove to be very vital. Best Wishes, Jean __________________ Stage 1, Grade 1, 3/30/05 Lumpectomy 4/15/05 - 6MM IDC Node Neg. (Sentinel node) ER+ 90% / PR-, Her2+++ by FISH Ki-67 40% Arimidex 5/05 Radiation 32 trt, 5/30/05 Oncotype DX test 4/17/06, 31% high risk TOPO 11 neg. 4/06 Stopped Arimidex 5/06 TCH 5/06, 6 treatments Herceptin 5/06 - for 1 yr. 9/06 Completed chemo Started Femara Sept. 2006