HER2 Support Group Forums - View Single Post - important discovery re how brain tumor recurs may have important implications in her2

Rich66 · 02-23-2010, 09:02 PM

Yes! More indication that blocking VEGF and HIF-1 simultaneously is the way to go. Zoledronic acid is thought to inhibit both...probably more if weekly...since metronomic dosing is thought to inhibit VEGF and HIF-1. Milk thistle and IP-6 are thought to inhibit HIF-1.
More on VEGF and HIF-1 crosstalk HERE

02-23-2010, 09:02 PM	#2
Rich66 Senior Member Join Date: Feb 2008 Location: South East Wisconsin Posts: 3,431	Re: important discovery re how brain tumor recurs may have important implications in Yes! More indication that blocking VEGF and HIF-1 simultaneously is the way to go. Zoledronic acid is thought to inhibit both...probably more if weekly...since metronomic dosing is thought to inhibit VEGF and HIF-1. Milk thistle and IP-6 are thought to inhibit HIF-1. More on VEGF and HIF-1 crosstalk HERE __________________ Mom's treatment history (link)