HER2 Support Group Forums - View Single Post - increased CA125 but not CA 15-3

Cannon · 01-10-2010, 08:07 PM

CA-125 is very non-specific - just indicates inflammation in the abdomen somewhere - check it out, but may be completely unrelated.
"A number of benign conditions can cause elevations of the CA 125 level, including pregnancy, endometriosis, uterine fibroids (benign tumors), pancreatitis, normal menstruation, pelvic inflammatory disease, and liver disease. Benign tumors or cysts of the ovaries can also cause an abnormal test result. Increases can also be seen in cancers other than ovarian cancer, including malignancies of the uterine tubes, endometrium, lung, breast, pancreas, and gastrointestinal tract." (medicinenet.com)

01-10-2010, 08:07 PM	#6
Cannon Senior Member Join Date: Oct 2007 Posts: 203	Re: increased CA125 but not CA 15-3 CA-125 is very non-specific - just indicates inflammation in the abdomen somewhere - check it out, but may be completely unrelated. "A number of benign conditions can cause elevations of the CA 125 level, including pregnancy, endometriosis, uterine fibroids (benign tumors), pancreatitis, normal menstruation, pelvic inflammatory disease, and liver disease. Benign tumors or cysts of the ovaries can also cause an abnormal test result. Increases can also be seen in cancers other than ovarian cancer, including malignancies of the uterine tubes, endometrium, lung, breast, pancreas, and gastrointestinal tract." (medicinenet.com) __________________ Dx 8/06 Age 43 Stage IIIA multifocal throughout breast, largest tumor 5 cm, grade 3, comedo, ER+PR+HER+++ Neoadjuvant A/C 4X Dose Dense 11/06 Bilateral Mastectomy (no choice on the right, my choice on the left) Taxol+Herceptin weekly x12, continuing with Herceptin, finished one year in 12/07 33 Rads Femara for 5+ years, staying on (started with Arimidex, switched after about a month, much happier) Abnormal brain MRI shows no cancer, but "extensive white matter diease" - unknown cause BRCA negative - lots of cancer in my family survivor of thyroid cancer also have Crohn's disease CT and bone scan say NED as of 5/13 dx with severe cardiomyopathy 5/12 (likely due to chemo and Herceptin), ejection fraction in low 20's, now up to 40, went to 50, latest read 12/13 is back down to 35 1/13 Acute pancreatitis - are you kidding me? 9/13 started Humira for Crohn's. starting to have some energy again B12 and Vit D both needed supplementation Cataracts in both eyes noted 6/12 - surgery in the next 2-4 years? 4/14 Kidney stones/blockage/infection - related to Crohn's Disease 5/14 My aunt passed away - she was diagnosed after I was with Stage I - not Her2+, then Stage 4 for about one year 6/14 Scans - still NED, thank God. However, broken rib (I didn't notice) lots of bone degeneration osteopenia/osteoporosis. I also still have cardiomyopathy secondary to chemo.