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Old 01-09-2010, 08:52 AM   #4
Becky
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Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
Re: AI's, etc effect on estradiol

There is a trial (started about 4 yrs ago) studying 5 yrs of Arimidex vs Femara vs Aromosin. My cousin is in this trial (Arimidex arm) so there won't be alot of results for awhile AND IMHO, it is the sustained results that will be the most interesting as all 3 drugs do a great job in reducing circulating estrogen. It is how well you do after therapy concludes that is very important (much the same as chemotherapy outcomes).

I would not spend alot of time pondering the minute differences in these drugs but rather focus on quality of life. Are there debilatating side effects that may force a change so one does not experience severe joint pain etc. If you are on one drug and are feeling good, great! If not, change.
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Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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