[Joe]

Herceptin results were originally announced at the 1998 ASCO meeting and it was FDA approved in October 1998

Herceptin Adjuvant results were announced in June 2005 and FDA approval was in November 2006

Tykerb results were announced in June of2006, It was FDA appoved in March 2007.

All three drugs were fast tracked by the FDA. Also note that these drugs became available for compassionate use shortly after Genentech and GSK applied for approval.

Regards
Joe