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Becky · 11-09-2009, 03:47 PM

In general, the stats for brain mets seems really high. I always thought that 25% - 30% of Her2+ metastatic patients would eventually wind up with brain mets. However, the longer survival times of Her2+ patients due to new therapies (Herceptin and Tykerb etc) do allow for brain mets to develop since many chemos and therapies do not pass the blood brain barrier.

There's not much info to really go on otherwise.

11-09-2009, 03:47 PM	#2
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	Re: Input wanted In general, the stats for brain mets seems really high. I always thought that 25% - 30% of Her2+ metastatic patients would eventually wind up with brain mets. However, the longer survival times of Her2+ patients due to new therapies (Herceptin and Tykerb etc) do allow for brain mets to develop since many chemos and therapies do not pass the blood brain barrier. There's not much info to really go on otherwise. __________________ Kind regards Becky Found lump via BSE Diagnosed 8/04 at age 45 1.9cm tumor, ER+PR-, Her2 3+(rt side) 2 micromets to sentinel node Stage 2A left 3mm DCIS - low grade ER+PR+Her2 neg lumpectomies 9/7/04 4DD AC followed by 4 DD taxol Used Leukine instead of Neulasta 35 rads on right side only 4/05 started Tamoxifen Started Herceptin 4 months after last Taxol due to trial results and 2005 ASCO meeting & recommendations Oophorectomy 8/05 Started Arimidex 9/05 Finished Herceptin (16 months) 9/06 Arimidex Only Prolia every 6 months for osteopenia NED 18 years! Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"