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Re: 40% of lymph node mets are of a different ER positivity/negativity, her2 positivi
I have read that the Pathways activated and markers, chemicals secreted which make breast cancer cells home to lymph nodes rather than bone, liver, brain and lungs are different and that bone marrow cells are much more indicative of breast cancer stem cells and what they think ultimately kills a patient.
Bone marrow tumor cells do not seem to clear with most chemo--the bone marrow tumorcells seem to divide only rarely (are dormant like mold in a shower stall this makes them return when the environment is right even after using clorox) making them impervious to treatments which kill the most quickly dividing cells-- and
can be followed to see if they disappear with targeted therapy.
How many of you would be willing to accept a test which hurt for under two minutes and left you a bit sore for one to three days in order to perhaps learn whether the treatment you had undergone was working or not?
I think many more than the oncologists think. They seem to think patients would prefer the side effects of weeks chemotherapy that may or may not even providing ANY benefit for all the "unpleasantness" to undergoing a quick test without associated nausea, vomiting, hair loss, anemia, low white counts and infections, mouth sours, cognitive changes, etc which might spare them the wrong treatment and help get them on the right road to one which might benefit them.
Any opinions?
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