HER2 Support Group Forums - View Single Post - possible gentle long-term strategy for treatment of Stage IV

Rich66 · 11-01-2009, 12:28 PM

I was just going to ask if there is overall momentum towards metronomic. Mom may need to investigate this since Taxol, then navelbine seemed to not be doable on a regular schedule. I attributed the Taxol pain and neutropenia reaction to amplified dose due to impaired liver function at the time. But navelbine repeatedly knocked her wbc down and her schedule wound up being 1/2 to 1/3 the normal dosage...despite relatively normal liver function. So...the metronomic approach for standard chemos seems attractive if there isn't an effective targeted/CSC therapy available to her.

11-01-2009, 12:28 PM	#2
Rich66 Senior Member Join Date: Feb 2008 Location: South East Wisconsin Posts: 3,431	Re: possible gentle long-term strategy for treatment of Stage IV I was just going to ask if there is overall momentum towards metronomic. Mom may need to investigate this since Taxol, then navelbine seemed to not be doable on a regular schedule. I attributed the Taxol pain and neutropenia reaction to amplified dose due to impaired liver function at the time. But navelbine repeatedly knocked her wbc down and her schedule wound up being 1/2 to 1/3 the normal dosage...despite relatively normal liver function. So...the metronomic approach for standard chemos seems attractive if there isn't an effective targeted/CSC therapy available to her. __________________ Mom's treatment history (link)