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Jean · 10-12-2009, 10:08 PM

Hi Alice

HER2 status is not useful in guiding treatment for ductal carcinoma in situ (DCIS) because it is more common for DCIS to be HER2-positive than it is for invasive cancer to be HER2-positive (we don't yet know why this is).

But this is an area of active research. MD Anderson has a trial for patients to receive one dose of herceptin. Who knows what the future will bring? Maybe women will be treated at the stage of DCIS if tested and are her2...maybe it will stop any breast cancer in the very earliest stage. Interesting thought hey?

For the most Alice dr. are not testing DCIS at this time.
But I would guess if the patient requests the test
and there is enough tissue to sample you could have the DCIS tested for Her2 positive.

Regards,
Jean

10-12-2009, 10:08 PM	#13
Jean Senior Member Join Date: Oct 2005 Location: New Jersey Posts: 3,154	Re: We need to know.... Hi Alice HER2 status is not useful in guiding treatment for ductal carcinoma in situ (DCIS) because it is more common for DCIS to be HER2-positive than it is for invasive cancer to be HER2-positive (we don't yet know why this is). But this is an area of active research. MD Anderson has a trial for patients to receive one dose of herceptin. Who knows what the future will bring? Maybe women will be treated at the stage of DCIS if tested and are her2...maybe it will stop any breast cancer in the very earliest stage. Interesting thought hey? For the most Alice dr. are not testing DCIS at this time. But I would guess if the patient requests the test and there is enough tissue to sample you could have the DCIS tested for Her2 positive. Regards, Jean __________________ Stage 1, Grade 1, 3/30/05 Lumpectomy 4/15/05 - 6MM IDC Node Neg. (Sentinel node) ER+ 90% / PR-, Her2+++ by FISH Ki-67 40% Arimidex 5/05 Radiation 32 trt, 5/30/05 Oncotype DX test 4/17/06, 31% high risk TOPO 11 neg. 4/06 Stopped Arimidex 5/06 TCH 5/06, 6 treatments Herceptin 5/06 - for 1 yr. 9/06 Completed chemo Started Femara Sept. 2006 Last edited by Jean; 10-12-2009 at 10:19 PM..