HER2 Support Group Forums - View Single Post - paclitaxel derivative that crosses blood-brain-barrier being developed

Rich66 · 09-24-2009, 08:06 PM

Hmmm. No mention of efficacy?

"a 19-amino acid peptide (angiopep-2) was developed that binds to low density lipoprotein receptor-related protein (LRP) receptors at the BBB and has the potential to deliver drugs to brain by receptor-mediated transport."

Assuming this does have efficacy, I wonder if this process could be utilized to deliver other agents, like vitamin H and all the others.

09-24-2009, 08:06 PM	#2
Rich66 Senior Member Join Date: Feb 2008 Location: South East Wisconsin Posts: 3,431	Re: paclitaxel derivative that crosses blood-brain-barrier being developed Hmmm. No mention of efficacy? "a 19-amino acid peptide (angiopep-2) was developed that binds to low density lipoprotein receptor-related protein (LRP) receptors at the BBB and has the potential to deliver drugs to brain by receptor-mediated transport." Assuming this does have efficacy, I wonder if this process could be utilized to deliver other agents, like vitamin H and all the others.