[Pam P]

Kavy - I hear the anxiety in your writing about changing chemos. I understand the feeling very well. Each time I have to start a new combo I fear what the side effects are going to do to me. I have not had ixempra, but from what I read on this site it's not an easy one (like any are!) so you have done well to manage it for almost a year. I was on xeloda/herceptin for about 3 yrs, then xeloda/tykerb for a few months. I did have the hand/foot problem, sometimes very painful, but all in all I felt great otherwise on this combo. I didn't notice any difference in s/e switching from the x/herc. to x/tykerb. When my onc. reduced the dose of xeloda my feet were much better. I've heard of people using some henna treatment on their feet when on xeloda which I didn't know about when I was on it. If I was to go back on xeloda I'd check that out. Google it. Also maybe xeloda will be easier on you this time - or at least easier than the ixempra and you'll be able to gain back some of the stamina that you wrote is compromised. Let me know how the new combo is working for you. I hope it goes super and pushes the progression back to remission.