[R.B.]

Hi Michka,

CRP is a a marker of inflammation. CRP is also considered a marker for cardiac disease.https://www.blogger.com/comment.g?bl...84564831125592 Omega 6 increases inflammation.

Oestrogen in women increases their ability to make the long chain omega-3 fats like DHA and EPA from the plant-based Omega three linolenic acid. Women have a very high need of long chain Omega threes. Women have smaller more neuron dense brains with more sophisticated connections. DHA is essential to brain health and the maintenance of healthy neurons. DHA is also essential to many other functions in the body including the fertility cycle. Omega six ultimately controls the ability of the body to make the hormones.

Fats have an important role to play in the risk of breast cancer. Omega six derivative has been shown to promote HER2 expression. these two trials give an indication of the importance of fats in breast cancer. The link below called the Greek diet contains many more.

http://annonc.oxfordjournals.org/cgi...ull/15/11/1719

http://journals.lww.com/eurjcancerpr...ega__3.11.aspx


This should be an essay, but I will try and put it succinctly.

Omega three which you have probably heard of has a sibling fat called Omega six. A significant number of trials and papers suggests that Omega three reduces the risk of breast cancer and Omega six increases it.


http://her2support.org/vbulletin/sho...ght=greek+diet


Commonly used in vegetable oils contain a very large proportion of plant-based Omega six called linoleic acid. Omega six is found in small quantities in all parts and in high quantities in plant reproductive material like seed nuts and corn.

Omega three on the other hand generally exerts anti-inflammatory influence in the body. The plant-based Omega three is found in small quantities in all plants, and in quantity in a very limited number of seats like flax.

Animals and humans take the plant-based fats and turn them into longer fats of the same of families. These longer fats are used to make families of chemicals. The Omega six chemicals are very inflammatory. The Omega three chemicals are anti-inflammatory.

Our modern diet is heavily in balanced in favour of Omega six and generally lacks Omega threes which makes the body very much more prone to inflammation.

We make things worse because we feed our animals on grains which distorts their Omega 3:6 profile as well. A factory chicken fed on grain produces eggs with 10 times as much Omega six as Omega three, whereas a true farm fed chicken will produce eggs with a balanced Omega 3:6 ratio. The distortion of these ratios goes through the food chain.

The biggest source of Omega six is vegetable oils. The common vegetable oils like sunflower grapeseed safflower soy peanut etc are all between 50 and 70% Omega six. Our intake of Omega six has increased from 1/2 to 2% of calories to 10% and higher in the modern diet. Intakes of Omega three have substantially decreased. Many women have woefully low intakes of long chain Omega three DHA.

Reducing the intake of plant-based Omega six and increasing the intakes of plant-based Omega three , and the long chain Omega three found in fish oil will help to reduce inflammation and so CRP.

There are a number of trials that suggest Omega threes reduce CRP and Omega sixes increase CRP.

The Greek diet thread above shows that Omega three and six also have big roles in determining the risk of breast cancer.

There is also evidence that drugs that block inflammation like NASIDs reduce the risk of breast cancer. The Omega three fat DHA which is found in fish has been shown to be more effective than some NASIDs.

Here are some links to some trials that suggest that Omega threes reduce CRP and Omega sixes increase CRP.

Fish oil can thin the blood and may have adverse effects for some are on medication for heart conditions, so please discuss significant dietary changes with your doctor.

Fish and shellfish are the place to start as they contain both long chain Omega threes and important minerals that are essential to body function. Seaweed is also a good source of minerals and iodine.

I have written a book on the subject. it is not very well edited, but the underlying science is generally good and it hopefully explains why the Omega 3:6 balance is so important. I have spent a year totally rewriting it and the new version is being professionally edited and hopefully a huge improvement. The title is intended to be interesting and controversial but was probably a mistake. The book contains over 700 references. The revised version will hopefully be available towards the end of this year or the beginning of the next. http://www.amazon.com/Omega-Six-Devi.../dp/0955707404 http://www.amazon.co.uk/Omega-Six-De...9517186&sr=8-1


C-reactive protein, dietary n-3 fatty acids, and the extent of coronary artery disease
http://cat.inist.fr/?aModele=afficheN&cpsidt=14104433

DHA Supplementation Decreases Serum C-Reactive Protein and Other Markers of Inflammation in Hypertriglyceridemic Men1–3,
http://jn.nutrition.org/cgi/content/abstract/139/3/495
Increased alpha-linolenic acid intake lowers C-reactive protein, but has no effect on markers of atherosclerosis. http://www.ncbi.nlm.nih.gov/pubmed/15220952

N-3 Fatty Acid Enriched Egg Decreases C-Reactive Protein in Healthy Adults
http://www.fasebj.org/cgi/content/me...ct/21/6/A740-b

Dietary -linolenic acid decreases C-reactive protein, serum amyloid A and interleukin-6 in dyslipidaemic patients
http://www.ingentaconnect.com/conten...00002/art00427

Isomer-specific effect of conjugated linoleic acid on inflammatory adipokines associated with fat accumulation in 3T3-L1 adipocytes.
http://www.ncbi.nlm.nih.gov/pubmed/17004891