Re: Naturally Preventable Metabolic syndrome and Breast Cancer
Thanks for this thread. I very much hope they pursue this... I hope that someday we will have endocrinologists sitting in on each one of our therapy planning sessions. - A.A.
"Researcher Tim Byers, M.D., M.P.H., associate dean of the Colorado School of Public Health and interim director of the University of Colorado Cancer Center, points out that these findings could help explain why being overweight is a known risk factor for postmenopausal breast cancer.
"We have assumed that the relationship between weight and breast cancer risk is due to increased circulating estrogens among postmenopausal women who are overweight or obese," he said in a media statement. "An alternative explanation is explored here: that some other aspect of the metabolic syndrome might be involved, such as growth-stimulating effects of insulin, or insulin-like growth factors."
Dr. Byers added that additional research is needed to study specific ways in which the metabolism of the female hormone estrogen metabolism is tied to the metabolic syndrome. "Though estrogens are produced in adipose (fat) tissues, just how these are metabolized in various subgroups of women needs better study. In addition, the hyper-inflammatory state of obesity and the metabolic syndrome need to be better described relative to cancer risk."
|