HER2 Support Group Forums - View Single Post - Vaccine Therapy in Treating Patients With Breast Cancer

Becky · 07-29-2009, 05:48 PM

This is the E75 trial. There (IMHO) are criteria problems with this trial. They test you and your immune system and only accept people who they believe will respond. All others are in the control group.

Secondly, I am afraid of vaccine trials that target Her2. (More on this later). I wish they would target something that cancer cells possess but normal cells do not. Remember that the heart is loaded with Her2 which is why the heart is affected (for some) by Herceptin. You can stop taking Herceptin if need be but a vaccine can't be stopped once injected. Your own body can "kill" your heart and other organs with naturally high Her2. Just my humble opinion. Really look and investigate the criteria of this trial It is extremely lopesided on how they pick their participants (besides the target factor)

07-29-2009, 05:48 PM	#4
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	Re: Vaccine Therapy in Treating Patients With Breast Cancer This is the E75 trial. There (IMHO) are criteria problems with this trial. They test you and your immune system and only accept people who they believe will respond. All others are in the control group. Secondly, I am afraid of vaccine trials that target Her2. (More on this later). I wish they would target something that cancer cells possess but normal cells do not. Remember that the heart is loaded with Her2 which is why the heart is affected (for some) by Herceptin. You can stop taking Herceptin if need be but a vaccine can't be stopped once injected. Your own body can "kill" your heart and other organs with naturally high Her2. Just my humble opinion. Really look and investigate the criteria of this trial It is extremely lopesided on how they pick their participants (besides the target factor) __________________ Kind regards Becky Found lump via BSE Diagnosed 8/04 at age 45 1.9cm tumor, ER+PR-, Her2 3+(rt side) 2 micromets to sentinel node Stage 2A left 3mm DCIS - low grade ER+PR+Her2 neg lumpectomies 9/7/04 4DD AC followed by 4 DD taxol Used Leukine instead of Neulasta 35 rads on right side only 4/05 started Tamoxifen Started Herceptin 4 months after last Taxol due to trial results and 2005 ASCO meeting & recommendations Oophorectomy 8/05 Started Arimidex 9/05 Finished Herceptin (16 months) 9/06 Arimidex Only Prolia every 6 months for osteopenia NED 18 years! Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"