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I've been taking Arimidex for over a year now.........bone and joint pain SEs are tolerable. My tumor was 90% ER+ and 60% PR+ and Her2++++..........my feeling is that the Arimidex is helping to keep the extra estrogen in my body in check (I'm post-menopausal, but being 30 pounds overweight is the culprit in the extra estrogen.) Even though my onc said that the motor behind the tumor's growth was the Her2neu aberration - I cannot discount the ER+ status. I also read somewhere (sorry but I don't have a link) that Her2 status can change with recurrences.......so I'm following my onc's advice and staying on Arimidex as long as my quality of life doesn't suffer (swimming helps). One other added benefit I've noticed with Arimidex - it has reduced the size of my endometrial lining and uterine fibroid (had these problems before the BC)..........the overload of post-menopausal estrogen is NOT a good thing in my mind!
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xxoo
Kathy
2/5/08 - dx age 53, post-menopausal;
IDC Stage 1, Grade 1
ER+ 90% /PR+ 90% /Her2++++, BRAC1 & 2 neg
3/5/08 - mast with muscle-sparing free tram;
0/7 nodes clear; Stage 1 lymphedema in right arm
3/11/08 - MRSA infection in abdomen causes large hernia
4/11/08 - Oncotype DX score 22 (intermediate)
4/12/08 - Muga score 67%
4/23/08 - Chemo, Navelbine and Herceptin every 2 weeks
8/20/08 - Last Navelbine infusion! Yay!
1/22/09 - First mammo since dx - unaffected breast CLEAR!
1/30/09 - Second Muga score 63%
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