HER2 Support Group Forums - View Single Post - Her-2 and hormone therapy?

Rich66 · 07-22-2009, 11:19 AM

I posted this before
http://her2support.org/vbulletin/showthread.php?t=38998

but I want to mention that it suggests her2 therapy can upregulate ER pathways. So...your biospy might read one thing now but actual ER activity might catually be increased as you get Herceptin. There's also the issue of the real accuracy of a biospy that is inherently limited to some degree.

07-22-2009, 11:19 AM	#27
Rich66 Senior Member Join Date: Feb 2008 Location: South East Wisconsin Posts: 3,431	I posted this before http://her2support.org/vbulletin/showthread.php?t=38998 but I want to mention that it suggests her2 therapy can upregulate ER pathways. So...your biospy might read one thing now but actual ER activity might catually be increased as you get Herceptin. There's also the issue of the real accuracy of a biospy that is inherently limited to some degree.