Thread: Her2 and BRCA
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Old 07-16-2009, 11:46 AM   #10
harrie
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Join Date: Mar 2007
Location: Hilo, Hawaii
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Brenda, did your mother or father have cancer? How about their siblings?

I had a very strong family history. My mother had bc and died at 69 yrs old. Her sister (my aunt) had bc and died even younger. Their dad (my grandfather) had pancreatic cancer. Having the BRCA2 increases chances of getting pancreatic, colon, and melenoma along with bc.

If your parents have not had a history of any of these cancers, your chances and your sister's chances are prob very minimal of carrying the gene despite the fact that you had bc and being HER2 to me is insignificant.
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*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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