Did she have serum Her2 test? What chemo is she getting? Is she getting Zometa as well? There has been some studies showing timing Zoledronic acid infusions after chemo can have synergy. If she is getting both, see if she can get them in that order. I started a thread on bisphosphonates in articles:
http://her2support.org/vbulletin/showthread.php?t=39563