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Old 06-21-2009, 05:39 AM   #7
jml
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Join Date: Dec 2006
Posts: 415
Welcome, Mena~
Though this is a club we are all reluctant to have to join, you will find not only a great deal of information & guidance here, but friendship, compassion & support.
I was Stage IV with liver mets since my primary dx in May 2002, even progressing to "innumerable, immeasureable" after not responding to Navelbine/Herceptin.
Ultimately Taxol/Herceptin got me to NED for a year, but after 1 met resurfaced, we tried TCH. That was effective for a bit but ultimately once we were able to isolate the met to just my L lobe, I had a liver resection & have been NED in my liver ever since.
Since your doc is pleased with the progress you've made thus far, maybe he'll consider dropping the Carbo? That carbo was really tough for me-Ugh!I hated it. I found Taxol/Herceptin really tolerable.
I've also been on Gemzar/Herceptin for 2 recurrences, but that wasn't been able to hold the beast back for very long. Now I'm Tykerb/Xeloda for 2 weeks & so far doing pretty well.
Don't lose hope! The right combo is out there for you, we just have to give your body a chance to rest & recuperate, then get back in there & start swinging with some new ammo!
Keep us posted on how you're doing, ok?

Keep the Faith~
Jessica

Dx - 5/17/2002 @33yo ;Stage IV - IDC + liver met;
Lumpectomy, 12/12+ nodes; er/pr-, Her2+++
Tx1 - Navelbine+Herceptin x 8 wks; No response, progression - single liver met to "innumerable/immeasureable"
Tx2 - ISIS 2504 - clinical trial x 6mos
Taxol + ISIS (continuous IV);partial response.
Tx3 - Taxol+Herceptin x 13 weeks
NED
NED 9/11/03-9/17/04, then single liver met recurrence.
9/04-Recurrence 1- Taxol+Herceptin x 4 weeks prior to RFA, but NED again, cxl RFA.
12/04 -Recurrence 2 - single liver met
1/05 - RFA - partial response
2/05 - Abraxane+Herceptin x 9 weeks;No response due to improper dosing(?)
3/05 - Taxol/Carbo/Herceptin to NED again.
11/05 - Recurrence 3 - same single liver met
12/05 - Right hepatectomy-55% liver removed. Success. NED in liver ever since.
2/06 - Recurrence 4 -single lesion in L breast again
3/06 -excisional biopsy. 1cm IDC, extensive high grade DCIS.
No tx due to liver still healing post hepatectomy, follow with Herceptin & scans to keep an eye on DCIS
12/06- L mastectomy w/ reconstruction 3/07 & 8/07
10/07 - Recurrence 5 - Supraclav nodes
Tx4 -Gemzar+Herceptin, til NED 3/08.
9/08 -Recurrence 6 -Supraclav nodes again.Rads1 - x 7wks
10/08 - Acute Renal Failure - ICU x4 days, hospital 1 week,
stents in ureters/kidneys x 4mos.still no known cause???
10/08 - Recurrence 7 -Sternal nodes; supraclav -NED
Tx5 - repeat Gemzar+Herceptin; NED in 1/09; finish GH cycle to 3/09.
4/09 - PET scans shows recurrence 8 in sternal nodes...progression while on GH cycle.
6/09 - Tykerb/Xeloda...Yay! I have The Rash
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