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aromatase inhibitor=no estrogen=abdominal fat/obesity
Hi all, found this, thought it was worth posting:
Obesity continues to rise in the United States and throughout the world. Both leptin from fat cells and insulin from pancreatic B cells are created in direct proportion to body fat. Obese persons have higher levels of these two hormones than lean individuals. Recent studies show that another hormone, estrogen, also has a similar affect. When estrogen receptors in the hypothalamus of rats were destroyed, female rats ate more food, burnt less energy and became obese. Research suggests a link between estrogen and obesity, especially the dangerous accumulation of abdominal fat linked to cardiovascular disease, type-2 diabetes mellitus, and certain cancers. The abstract was submitted by Deborah J. Clegg, PhD, Assistant Professor of Psychiatry, Obesity Research Center, at the University of Cincinnati Academic Health Center, to the 234th national meeting of the American Chemical Society on August 20, 2007. Her findings will assist scientists in developing new hormone replacement therapies.
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Donna in the Sierra Foothills of California
Diagnosed 6/7/06 invasive ductal carcinoma/ductal carcinoma in situ
Lumpectomy 6/21/06
Pathology: Er 99% Pr 10% Her2/neu 3+
DNA Index 1.0
S-Phase 3/High
Primary Tumor 2.4 cm Sentinel Node Tumor 2.1cm
A/C/T+ Herceptin + rads + Arimidex
stopped Herceptin after 7 mos. due to low MUGA
Surgery for thickened uterine tissue May 2008 - conclusion: side effect of Arimidex
Switched from Arimidex to Femara - joint/tendon problems significantly better!
2 year mark Pet scan and Echo shows all clear!
5 year mammogram with ultrasound shows no sign of cancer - yay!
11 years, 11 months new breast cancer - found lump
Mastectomy 4/30/2018
Pathology: Er99%, PR 28%, Her2 negative! (new type)
Faslodex
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