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Hopeful · 11-04-2008, 07:24 AM

Thanks to all for your responses! Pooling information is so helpful. I do exercise pretty regularly, walking 45 minutes a day on my treadmill at 3.2 mph on a no. 4 incline (out of 10) around 4-5 times per week. My wrist gets a little work out from my knitting. I work a "desk" job, though I do get up and walk around the building when I need to confer with co-workers rather than phone or e-mail them. I get stomach problems from the asprin and asprin like NASAID's, and think tylenol is too hard on the liver, so I stay away from those meds for this issue.

I went back to the Arimidex last night, and, already, I see a HUGE difference: NO ankle stiffness this morning, and the wrist is 50% better. It will probably be 100% by tomorrow. This is the same kind of recovery I saw from the Arimidex symptoms when I switched back to Femara last year. I am thinking there is just a toxicity level for each of these drugs that builds up until I hit the wall. I am going to talk to my onc at my next visit about continuing to alternate between the two as a strategy to get through 5 years of tx.

Sassy, I am also intrigued by the "Lasix phenomenon" you described, and would be interested to hear from others with a similar experience as well.

I am glad that so many of our members here have found ways to deal with these issues, and appreciate your sharing them.

Hopeful

11-04-2008, 07:24 AM	#7
Hopeful Senior Member Join Date: Aug 2006 Posts: 3,380	Thanks to all for your responses! Pooling information is so helpful. I do exercise pretty regularly, walking 45 minutes a day on my treadmill at 3.2 mph on a no. 4 incline (out of 10) around 4-5 times per week. My wrist gets a little work out from my knitting. I work a "desk" job, though I do get up and walk around the building when I need to confer with co-workers rather than phone or e-mail them. I get stomach problems from the asprin and asprin like NASAID's, and think tylenol is too hard on the liver, so I stay away from those meds for this issue. I went back to the Arimidex last night, and, already, I see a HUGE difference: NO ankle stiffness this morning, and the wrist is 50% better. It will probably be 100% by tomorrow. This is the same kind of recovery I saw from the Arimidex symptoms when I switched back to Femara last year. I am thinking there is just a toxicity level for each of these drugs that builds up until I hit the wall. I am going to talk to my onc at my next visit about continuing to alternate between the two as a strategy to get through 5 years of tx. Sassy, I am also intrigued by the "Lasix phenomenon" you described, and would be interested to hear from others with a similar experience as well. I am glad that so many of our members here have found ways to deal with these issues, and appreciate your sharing them. Hopeful