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thanks for all your comments. i had such an easy time with herceptin...no problems at all (except if you want to count that it stopped working lol). i have actually stopped even my multivitamin and b-complex because they both contained folic acid. thing is i was very deficient in that so i don't know. i'll ask rheumy tomorrow. also i've been on nexium for years. brenda, what is the digestive enzyme you're taking? maybe that would help me. i need to do something because i can't live like this for the duration. gm
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