[Barbara2]

I can tell you about my "treatment" with Celebrex. After finishing chemo, my onc said he would start me on Arimidex and also Celebrex. This was spring 2003; he said there was some research suggesting that celebrex may shut down the Cox 2, plus the drug may help with any aches/pains that may arise from taking Arimidex.

I took 400 mg twice daily, which is quite a healthy dose, I believe. I took it for about 13 months and finally figured out it was making me ill. (Of course not everyone may respond that way.) I had total brain fog and big time lethargy. As soon as I stopped the Celebrex I felt MUCH better.

But in the meantime, I hoped that I had taken it long enough, plus at the same time as Arimidex, to perhaps do some good.

This is the comment I got from Dr. Pegram when I asked him in the spring of 07, if Celebrex was worth trying:

If you do it sporadically once in a while, it’s not going to help at all. The standard dose of Celebrex doesn’t work in breast cancer. There’s still some question about the high dose, but these drugs could cause cardio-vascular mortality so if you don’t have metastatic disease I probably wouldn’t recommend it. High dose: 400 bid. If you’re in remission, you should not take Cox 2 inhibitors.

Hope this helps a little!