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" HER2+ cancers overexpress topo2a about 1/3 of the time. HER2 negative (he made mention of HER2 "normal", rather than negative) cancers never overexpress topo2a."
Hmmm. Does this mean testing for topo2a could be another way to confirm Her2 positivity when FISH results are equivocal? Is topo2 readily testable? I've never heard of it.
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