HER2 Support Group Forums - View Single Post - Anyone heard of subcutaneous fibrous scar tissue?

Lani · 09-20-2008, 05:18 PM

literature citing the combination of trental (pentoxyfilline) and vitamin E as helpful for post-radiation fibrosis, even when given long after the radiation was given and even when given long after the fibrosis developed.

Anyway you could give the combination a trial to see if it worked before opting for surgery? Surgery usually causes scarring of its own and after radiation is given to an area, and after surgery disturbs an area its blood supply may be diminished, which also may contribute to the tendency to heal with more rather than less scar tissue, as I understand it.

I will post the abstracts for a couple of the articles--the same combination seems to help with radiation for head and neck cancer, which is where I first became aware of it (reading to help someone with a parotid tumor)

I personally know of two people who have done exceptionally well on the combination,
with minimal scarring after either very superficial (electron-beam) or very "dose-dense" ie accelerated course with big fractions, radiation therapy.

09-20-2008, 05:18 PM	#2
Lani Senior Member Join Date: Mar 2006 Posts: 4,782	no personal experience, but there are multiple reports in the literature citing the combination of trental (pentoxyfilline) and vitamin E as helpful for post-radiation fibrosis, even when given long after the radiation was given and even when given long after the fibrosis developed. Anyway you could give the combination a trial to see if it worked before opting for surgery? Surgery usually causes scarring of its own and after radiation is given to an area, and after surgery disturbs an area its blood supply may be diminished, which also may contribute to the tendency to heal with more rather than less scar tissue, as I understand it. I will post the abstracts for a couple of the articles--the same combination seems to help with radiation for head and neck cancer, which is where I first became aware of it (reading to help someone with a parotid tumor) I personally know of two people who have done exceptionally well on the combination, with minimal scarring after either very superficial (electron-beam) or very "dose-dense" ie accelerated course with big fractions, radiation therapy.