HER2 Support Group Forums - View Single Post - her2+ bc with lymphocytes relapses less...

Becky · 09-19-2008, 05:33 AM

Hi Robin

Is it that the lymphocytes are associated with the tumor or that the lymphs are those measured in the bloodstream (as I could not access the article). The reason I ask is twofold. Firstly, my counts on lymphs have always been on the high side and continue to be. I blame this more on allergies than anything else. Secondly, I used Leukine instead of neulasta/neupogen and this boosts everything including monocytes that feed the lymphocyte stream so during chemo, my lymphs prior to treatments were astronomical. I was extremely pleased with this because the lymph phenomenon is what you want for self vaccination (and why Leukine is used to boost the immune response of all the Her2 vaccine trials).

I am sure this was an interesting article. Is there any way you can cut and paste.

For the record, I used Leukine in order to try to self vaccinate as many studies with the drug suggested and proved (to some extent) because at that time, Herceptin was not available in the adjuvant situation until my chemo was 4 months over.

09-19-2008, 05:33 AM	#2
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	Hi Robin Is it that the lymphocytes are associated with the tumor or that the lymphs are those measured in the bloodstream (as I could not access the article). The reason I ask is twofold. Firstly, my counts on lymphs have always been on the high side and continue to be. I blame this more on allergies than anything else. Secondly, I used Leukine instead of neulasta/neupogen and this boosts everything including monocytes that feed the lymphocyte stream so during chemo, my lymphs prior to treatments were astronomical. I was extremely pleased with this because the lymph phenomenon is what you want for self vaccination (and why Leukine is used to boost the immune response of all the Her2 vaccine trials). I am sure this was an interesting article. Is there any way you can cut and paste. For the record, I used Leukine in order to try to self vaccinate as many studies with the drug suggested and proved (to some extent) because at that time, Herceptin was not available in the adjuvant situation until my chemo was 4 months over. __________________ Kind regards Becky Found lump via BSE Diagnosed 8/04 at age 45 1.9cm tumor, ER+PR-, Her2 3+(rt side) 2 micromets to sentinel node Stage 2A left 3mm DCIS - low grade ER+PR+Her2 neg lumpectomies 9/7/04 4DD AC followed by 4 DD taxol Used Leukine instead of Neulasta 35 rads on right side only 4/05 started Tamoxifen Started Herceptin 4 months after last Taxol due to trial results and 2005 ASCO meeting & recommendations Oophorectomy 8/05 Started Arimidex 9/05 Finished Herceptin (16 months) 9/06 Arimidex Only Prolia every 6 months for osteopenia NED 18 years! Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"