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Soccermom2006 · 09-12-2008, 10:19 AM

"The Bottom Line: Do Not Administer Any SSRI With Tamoxifen
The future is exciting with the possibility of developing truly customized, 100%-effective therapies for our patients. For the present, however, besides entering our patients onto well-designed clinical trials asking important questions, we must not encumber our currently available therapies with combinations of drugs that effectively make them a placebo. The bottom line is this: Do not administer any SSRIs (fluoxetine [Eli Lilly and Company, Indianapolis, IN], paroxetine [Paxil, GlaxoSmithKline, Pittsburgh, PA], sertraline [Zoloft, Pfizer, New York, NY], citalopam [Celexa, Forest Laboratories, Inc., New York, NY], or escitalopam [Lexapro, Forest Laboratories, Inc.]) concurrently with tamoxifen. When in doubt, check it out. Sources are listed in Table 3. However, because this interaction is so recently documented, it is not yet included in many of the standard references. Be the first to tell your colleagues. "
http://www.jopasco.org/cgi/content/full/1/4/155 (2005)

http://jop.ascopubs.org/cgi/content/full/2/2/100 more recent (2006)

Thought that this might be of interest...
Marcia

09-12-2008, 10:19 AM	#1
Soccermom2006 Senior Member Join Date: Jul 2006 Posts: 59	For those on SSRI's and Tamoxifen... "The Bottom Line: Do Not Administer Any SSRI With Tamoxifen The future is exciting with the possibility of developing truly customized, 100%-effective therapies for our patients. For the present, however, besides entering our patients onto well-designed clinical trials asking important questions, we must not encumber our currently available therapies with combinations of drugs that effectively make them a placebo. The bottom line is this: Do not administer any SSRIs (fluoxetine [Eli Lilly and Company, Indianapolis, IN], paroxetine [Paxil, GlaxoSmithKline, Pittsburgh, PA], sertraline [Zoloft, Pfizer, New York, NY], citalopam [Celexa, Forest Laboratories, Inc., New York, NY], or escitalopam [Lexapro, Forest Laboratories, Inc.]) concurrently with tamoxifen. When in doubt, check it out. Sources are listed in Table 3. However, because this interaction is so recently documented, it is not yet included in many of the standard references. Be the first to tell your colleagues. " http://www.jopasco.org/cgi/content/full/1/4/155 (2005) http://jop.ascopubs.org/cgi/content/full/2/2/100 more recent (2006) Thought that this might be of interest... Marcia