[Gerri]

Hi Cheryl,

It was not so long ago that I was posing the same question. You can probably do a search and come up with quite a few threads on this subject. I was 52 at the time of my dx (you look to be much younger) but still pre-menopausal. My onc put me on Tamoxifen and I stayed on it for two years. I was getting concerned about being a poor metabolizer because I never experienced hot flashes while taking the drug. At my two year mark I was getting ready to force my body into menopause when low and behold I was finally there! I am now on Femara and doing remarkably well.

There is a lot of controversy regarding Tamox vs AIs in the HER2+ population. My onc felt that all the data was not yet in supporting an AI over Tamoxifen - I had this discussion with her every time I had an appointment. At first I was very comfortable staying on Tamoxifen, but as time went on I was getting anxious to make the switch. I never asked about the test to determine if I was resistant to Tamoxifen, but I would encourage you to have it done. However, from what I understand from other threads on this board, taking Tamoxifen while receiving Herceptin is beneficial so you are probably safe with it for now. I believe your age and degree of positivity in your ER/PR status come into play as well. Hopefully Becky and others will see this thread and give you more information.

Good luck with your decision making; I know it can be overwhelming at times.