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Patricia,
I have been on Xeloda since Jan. I tolerated the first round fine, then it became increasingly difficult to walk and do ordinary tasks. There are three stages, to hand foot syndrome.( a brochure will detail or look up on internet). Anyway, I read on the internet that some Doctors are recommending one week on and one week off. My Doctor didn't have a problem with me trying that. It works better for me. I have had my dose lowered from 2000mg to 1800mg and may have to lower it again. The end of week one is rough. I totally agree with Sheila, flip lops or some smooth open shoes work best. Crocs are killers with all the little nubs. I use Specto Exema Cream for my hands and feet. (less greasy).
I also read that there was a trial to see if nicotine patches might close the capillaries sp? I tried it but I don't think it worked for me. Hope this helps. Hang in there,
Hugs,
Diana
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