HER2 Support Group Forums - View Single Post - Jean and others--for certain bc subtypes size and no. of lymph nodes , prognosis not

Lani · 07-05-2008, 03:37 PM

rather put "ENTREZ PUBMED" into google

Then put the PUBMEDID number(PMID, in this case 18600446) at the bottom of the abstract into the rectangular address bar and press return...voila!

Whether or not you can only get the abstract vs the whole article depends on whether it is open access or restricted.

Basal type breast cancer is a type of triple negative bc (ER-PR-her2-) which closely resembles cancer stem cells by being CD44+, CD24- and/or ALDH1+)

There are some triple negatives which are not basal and have better prognoses.

The HR (hazard ratio) for her2+ER+ vs her2+ er- were not entirely consistent
ie following a pattern you would expect probably because of the relatively small numbers. I will try to post part of the chart if I can manage it so you can.

By the way, there are different molecular subtypes of her2+ bc. Those that are ER- fall into the her2 subtype. Those that are ER+ are either put within
the title luminal B where they are felt to constitute 40-50% of luminal Bs or
according to Joel Gray,an incredible researcher who has invented at least four seminal research technique, anyone of which should have earned him the Nobel Prize--he was saluted at San Antonio this year, in a category of their own called luminal amplified.--among Dr. Gray's discoveries are the techniques FISH, CGH, rtPCR.

07-05-2008, 03:37 PM	#8
Lani Senior Member Join Date: Mar 2006 Posts: 4,782	I am lousy with links rather put "ENTREZ PUBMED" into google Then put the PUBMEDID number(PMID, in this case 18600446) at the bottom of the abstract into the rectangular address bar and press return...voila! Whether or not you can only get the abstract vs the whole article depends on whether it is open access or restricted. Basal type breast cancer is a type of triple negative bc (ER-PR-her2-) which closely resembles cancer stem cells by being CD44+, CD24- and/or ALDH1+) There are some triple negatives which are not basal and have better prognoses. The HR (hazard ratio) for her2+ER+ vs her2+ er- were not entirely consistent ie following a pattern you would expect probably because of the relatively small numbers. I will try to post part of the chart if I can manage it so you can. By the way, there are different molecular subtypes of her2+ bc. Those that are ER- fall into the her2 subtype. Those that are ER+ are either put within the title luminal B where they are felt to constitute 40-50% of luminal Bs or according to Joel Gray,an incredible researcher who has invented at least four seminal research technique, anyone of which should have earned him the Nobel Prize--he was saluted at San Antonio this year, in a category of their own called luminal amplified.--among Dr. Gray's discoveries are the techniques FISH, CGH, rtPCR.