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Barbara H. · 06-24-2008, 09:33 AM

Hi Joan,
I would still push for the Herceptin MCC DM1 trail (phase 1). The purpose of phase one is to test the dosages. Therefore you do not need to have measurable disease. I have bone mets that are not measurable. This is a great drug and I think you would have an excellent chance of getting rid of that nodule and any other systemic disease that is not yet visible. You can try xeloda anytime. However, this drug will not be available for a while.

The purpose of a phase II trial is to measure its effectiveness. That is why you need measurable disease. I would really try to get into the phase I trial if it is still open.

Good luck,
Barbara H.

06-24-2008, 09:33 AM	#8
Barbara H. Senior Member Join Date: Sep 2005 Location: Newton, MA Posts: 951	Phase I Hi Joan, I would still push for the Herceptin MCC DM1 trail (phase 1). The purpose of phase one is to test the dosages. Therefore you do not need to have measurable disease. I have bone mets that are not measurable. This is a great drug and I think you would have an excellent chance of getting rid of that nodule and any other systemic disease that is not yet visible. You can try xeloda anytime. However, this drug will not be available for a while. The purpose of a phase II trial is to measure its effectiveness. That is why you need measurable disease. I would really try to get into the phase I trial if it is still open. Good luck, Barbara H.