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Jean · 06-08-2008, 08:31 PM

Data on early stagers who were treated with herceptin/
and chemo plus herceptin is not in. I believe this will have an important impact on recurrence stats.

When I had my lumpectomy surgery at Cornell there was a study being done on patients that were early stage bc, node negative. The dr. were performing bone marrow biopsies to study dormant bc cells.

The mechanisms underlying tumor dormancy in breast
cancer remain poorly understood and this presents significant challenges to both experimental investigation and clinical management.

What makes the cancer sleep and what wakes it up?

In any event....as Maryann has proved "The stats can be /and will/be wrong..while we all share this nasty disease, we each live in our own DNA...and as Becky said, anything can happen any day of the week, so
enjoy each day and live it to the fullest. We are lucky in a sense, for we have learned through our bc dx. not to sweat the small stuff and most of all a deeper understanding of "What is really important" from day to day.

Hopefully the near future will bring us more details and answers.

"Each Day We Get A Little Bit Closer"
Jean

06-08-2008, 08:31 PM	#22
Jean Senior Member Join Date: Oct 2005 Location: New Jersey Posts: 3,154	Data on early stagers who were treated with herceptin/ and chemo plus herceptin is not in. I believe this will have an important impact on recurrence stats. When I had my lumpectomy surgery at Cornell there was a study being done on patients that were early stage bc, node negative. The dr. were performing bone marrow biopsies to study dormant bc cells. The mechanisms underlying tumor dormancy in breast cancer remain poorly understood and this presents significant challenges to both experimental investigation and clinical management. What makes the cancer sleep and what wakes it up? In any event....as Maryann has proved "The stats can be /and will/be wrong..while we all share this nasty disease, we each live in our own DNA...and as Becky said, anything can happen any day of the week, so enjoy each day and live it to the fullest. We are lucky in a sense, for we have learned through our bc dx. not to sweat the small stuff and most of all a deeper understanding of "What is really important" from day to day. Hopefully the near future will bring us more details and answers. "Each Day We Get A Little Bit Closer" Jean __________________ Stage 1, Grade 1, 3/30/05 Lumpectomy 4/15/05 - 6MM IDC Node Neg. (Sentinel node) ER+ 90% / PR-, Her2+++ by FISH Ki-67 40% Arimidex 5/05 Radiation 32 trt, 5/30/05 Oncotype DX test 4/17/06, 31% high risk TOPO 11 neg. 4/06 Stopped Arimidex 5/06 TCH 5/06, 6 treatments Herceptin 5/06 - for 1 yr. 9/06 Completed chemo Started Femara Sept. 2006 Last edited by Jean; 06-08-2008 at 08:40 PM..