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I had quite a few "oral" issues with Tykerb (although not the type you have described). Perhaps it does not agree with you. But there are many approaches they can use (benedryl etc.) if they really feel it is the right choice. I recently switched back to Herceptin - as they are not sure if the Tykerb quit working, if the Herceptin ever did quit working for sure etc. We are often exposed to "cutting edge drugs" and they just do not seem to have all the answers. I wish I had a definite one for you....perhaps your doc could consult with some physcians from other areas to see if they ran into this. Also, I do want to say that Tykerb was harder on me the 1st two months and then my body seemed to adjust to it for quite a while. I never won the frequent bouts with loose stools though. That is why I opted to switch back to Herceptin.
I wish you luck and I hope they get answers for you soon!
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Barb
10/03 Radical Mastectomy 3 cm tumor - 1/17 Nodes Stage II B, Her 2 +++ ER-/PR- 11/03 4 AC 4 Taxol 12/05 Stage IV - Lung met , Bone mets - Carbo, Taxotere, Herceptin 9/06 - 2 cm brain tumor 10/06 - Tumor removal surgery - Herceptin Halted 12/06 gamma knife tumor base.1/07 Navelbine/Herceptin 4/07 Rads to R femur 5/07 Stereotactic - new 2 cm brain tumor 4/07 Start Xeloda 5/07 Tykerb added 7/07 Brain MRI clean 10/07 .055 cm brain met found. 12/07 Stereotactic -1 cm brain tumor Start Tykerb 11/07 Abraxane/Herceptin 5/08 Cisplatin, Gemcitabine/Herceptin 6/08 Stereotactic to 1cm 9/08 Stereotactic repeat (growth). 11/08 Pet Scan Good but new tiny met on L lung/dead Brain surgery (no cancer cells found/scar tissue) 1/09 Chemo restarted 2/09 Pet Scan Bad - R larger very active/active L active lymph nodes both sides of chest MRI- mets slight increase 2/09 Start Doxil/Tykerb Treatment
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