HER2 Support Group Forums - View Single Post - brain mets update -- follow-up

Emmay · 06-06-2008, 02:14 PM

Thanks to each and every one for your kind words and thoughts.

PattyZ, thanks especially to you for sharing your course of therapies. I too had read about the concerns about Avastin, and worry about it, but also have read some reports that support its use for recurrent bc brain mets.

http://www.asco.org/ASCO/News/Cancer...eutersid=10596

http://www.abstract.asco.org/AbstView_55_34611.html

http://www.abstract.asco.org/AbstView_55_34386.html

(I have read that Ted Kennedy's doctors are considering Temodar and Avastin as a chemo combination for him.)

My sister is tolerating the Irinotecan/Avastin well so far --just fatigue the day following infusion. She is also continuing Xeloda.

I will be asking my sister's doctors about the possibility of trying Temodar again, but when she was taking Temodar and Sorafenib (which is also an antiangiogenesis agent) she did not tolerate it well, and was consistently losing 3-5 lbs/month.

A lot will depend on how her next MRI looks toward the end of the month.

You and your doctors have done a remarkable job juggling therapies and adjusting as needed -- it speaks well for your knowledge of your own body and following your instincts about what you need. You are inspirational; I wish you continuing success! - and will keep posting as we learn more.

Emmay

06-06-2008, 02:14 PM	#9
Emmay Senior Member Join Date: Apr 2006 Location: Boston Posts: 66	bc brain mets info from asco Thanks to each and every one for your kind words and thoughts. PattyZ, thanks especially to you for sharing your course of therapies. I too had read about the concerns about Avastin, and worry about it, but also have read some reports that support its use for recurrent bc brain mets. http://www.asco.org/ASCO/News/Cancer...eutersid=10596 http://www.abstract.asco.org/AbstView_55_34611.html http://www.abstract.asco.org/AbstView_55_34386.html (I have read that Ted Kennedy's doctors are considering Temodar and Avastin as a chemo combination for him.) My sister is tolerating the Irinotecan/Avastin well so far --just fatigue the day following infusion. She is also continuing Xeloda. I will be asking my sister's doctors about the possibility of trying Temodar again, but when she was taking Temodar and Sorafenib (which is also an antiangiogenesis agent) she did not tolerate it well, and was consistently losing 3-5 lbs/month. A lot will depend on how her next MRI looks toward the end of the month. You and your doctors have done a remarkable job juggling therapies and adjusting as needed -- it speaks well for your knowledge of your own body and following your instincts about what you need. You are inspirational; I wish you continuing success! - and will keep posting as we learn more. Emmay