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Old 06-06-2008, 08:15 AM   #4
doh2pa
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Join Date: Oct 2005
Location: Chadds Ford, Pa
Posts: 206
Hi Angela,

I took Tykerb for 8 months and did not have the specific mouth issues you have but did have lots of GI issues the last 4 months I was on it. Don't despair, please. I know it seems like herceptin stopped working for you, but it may work better in combo with the Navilbene. I've had an "on again, off again" relationship with Herceptin the last few years. It seems like alone it doesn't hold my disease at bay, but I did take it along with Navilbene and got a very good response. So if you can't tolerate Tykerb there are other options and combos to try.
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Donna
Diagnosed 2/04 - Invasive ductal - no clean margins
node negative - er+pr+, her2++
Mastectomy 4/04 - 4 rounds AC
9/05 - mets to liver treated with carbo/ixabipelone/herceptin
3/06 - complete remission
9/06 - new liver mets, starting Taxotere/Herceptin
1/07 -Liver mets stable, staying on Herceptin
5/07 - Liver, lung progression - starting T/X
12/07 - Liver, lung progression - starting weekly Navilbene/Herceptin
4/08 - Liver progression - started Abraxane, Carbo, Tykerb and Herceptin
7/08 - Liver Progression - started Gemzar, Avastin and Tykerb
10/08 - Liver progression - starting Doxil
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