Thread: well...
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Old 05-29-2008, 02:49 PM   #8
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
Thumbs up Cool!

Joy, I think this is great news! Is this the 3 week or the 1 week trial?

Either way, I hope you have some good books on tape or whatever now that you'll be joining the weekly DM1 day-trippers. They are very, well, anal (can I say that?) on this trial which is a good thing as the drug is so experimental. I'm glad they monitor everything so closely so they can get the dosage answers they need and keep us safe. Even though I had to get my last treatment pushed back

Of course, you've been round the block enough to know that everyone responds differently with respect to side effects. I started to list all the ones I've had in gory detail, but then I remembered you wanted ENcouragement, not DIScouragement!
So, I'll just say it is more toxic than regular herceptin but not as bad as chemo. In terms we can all understand, on the spectrum starting with lemonade --->margarita--->tequila shots, it's sort of a slushy weak maggie.

I know you will do great on this trial!
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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