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Hopeful · 05-29-2008, 01:03 PM

CLTann,

From what I have read, ER+ bc has a 2% per year risk of recurrence, that is additive each year, i.e., a person surviving 10 years has a 20% chance at that point. The risk of ER+ bc returning never goes away. Evidence from delayed hormone therapy trials and extended therapy trials has been positive to date, showing that hormone therapy can reduce this risk. ER- patients do have a drop off of recurrence after 5 years, which declines until 10 years, when the ER+ and ER- recurrence rates cross. The information was in the last quinquennial meeting results from the Early Breast Cancer Trialist Collaborative Group. This information, however, did NOT address Her2 positivity OR Herceptin - two variables that are very important to the outcome. I would not expect to see those kinds of statistics for quite some time.

Hopeful

05-29-2008, 01:03 PM	#32
Hopeful Senior Member Join Date: Aug 2006 Posts: 3,380	CLTann, From what I have read, ER+ bc has a 2% per year risk of recurrence, that is additive each year, i.e., a person surviving 10 years has a 20% chance at that point. The risk of ER+ bc returning never goes away. Evidence from delayed hormone therapy trials and extended therapy trials has been positive to date, showing that hormone therapy can reduce this risk. ER- patients do have a drop off of recurrence after 5 years, which declines until 10 years, when the ER+ and ER- recurrence rates cross. The information was in the last quinquennial meeting results from the Early Breast Cancer Trialist Collaborative Group. This information, however, did NOT address Her2 positivity OR Herceptin - two variables that are very important to the outcome. I would not expect to see those kinds of statistics for quite some time. Hopeful Last edited by Hopeful; 05-30-2008 at 06:31 AM.. Reason: clarification