HER2 Support Group Forums - View Single Post - predicting which her2+ breast cancer patients will get brain mets by primary tumor

Lani · 05-19-2008, 12:32 AM

Actually oncodx is a very simple test--it includes 21 genes including about 6 "housekeeping genes" not related to the likelihood breast cancer spread, if I remember correctly

The most important genes within it are easily tested separately (although most are measured in a different way with oncodx, ie by mRNA levels):
ER, PR, her2, GRB7 (next door neighbor to her2 on chromosome 17 which
some researchers feel may be the real culprit rather than her2 itself), Ki67.

SO far I think we've got 11, that leaves about 10. Will check them out when I can.

05-19-2008, 12:32 AM	#4
Lani Senior Member Join Date: Mar 2006 Posts: 4,783	No I don't think so Actually oncodx is a very simple test--it includes 21 genes including about 6 "housekeeping genes" not related to the likelihood breast cancer spread, if I remember correctly The most important genes within it are easily tested separately (although most are measured in a different way with oncodx, ie by mRNA levels): ER, PR, her2, GRB7 (next door neighbor to her2 on chromosome 17 which some researchers feel may be the real culprit rather than her2 itself), Ki67. SO far I think we've got 11, that leaves about 10. Will check them out when I can.