Here is a link to a study of neoadjuvant Herceptin, where patients who had not previously had chemo were given Herceptin without chemo prior to surgery:
http://clincancerres.aacrjournals.or...ull/10/17/5650
I think there is more than one study that looked at it, but this is the one I could most easily find. If I can find the links to any others, I will edit the post.
Hopeful