HER2 Support Group Forums - View Single Post - taxol & avastin

Sheila · 05-09-2008, 03:53 PM

Pam
I was on Herceptin, Taxol and Avastin for over 6 months, then dropped the Avastin due to elevated B/P and lack of FDA Approval....both have since resolved. I continued on Herceptin and Taxol, and just recently got a 6 week repreive from the Taxol....the Avastin for me was no problem, except for the elevated B/P...I ended up going on B/P meds for it...and am, still on it, although my B/P has come done to almost normal. I never really had a problem from the Taxol, other than being bald (my hair began to return while on Taxol) nose bleeds, bleeding gums and leg cramps...it was the Decadron that did a number on me....I will be going back on Taxol or Abraxane in a week so l will see...I am excited that my eyebrows are finally coming back...I WAS ON THE COMBO A TOTAL OF 6MONTHS, AND HAD GREAT RESULTS, THEN THE TAXOL CONTINUED WITH THE HERCEPTIN FOR ANOTHER 4 MONTHS. Now just Herceptin....this combo is very promising...I am however ER - PR -, not that it makes a difference. Good Luck...the first dose takes forever....the loading of the Avastin and the Taxol.

05-09-2008, 03:53 PM	#3
Sheila Senior Member Join Date: Aug 2003 Location: Morris, IL Posts: 3,507	Pam I was on Herceptin, Taxol and Avastin for over 6 months, then dropped the Avastin due to elevated B/P and lack of FDA Approval....both have since resolved. I continued on Herceptin and Taxol, and just recently got a 6 week repreive from the Taxol....the Avastin for me was no problem, except for the elevated B/P...I ended up going on B/P meds for it...and am, still on it, although my B/P has come done to almost normal. I never really had a problem from the Taxol, other than being bald (my hair began to return while on Taxol) nose bleeds, bleeding gums and leg cramps...it was the Decadron that did a number on me....I will be going back on Taxol or Abraxane in a week so l will see...I am excited that my eyebrows are finally coming back...I WAS ON THE COMBO A TOTAL OF 6MONTHS, AND HAD GREAT RESULTS, THEN THE TAXOL CONTINUED WITH THE HERCEPTIN FOR ANOTHER 4 MONTHS. Now just Herceptin....this combo is very promising...I am however ER - PR -, not that it makes a difference. Good Luck...the first dose takes forever....the loading of the Avastin and the Taxol. __________________ "Be kinder than necessary, for everyone you meet is fighting some kind of battle." Hugs & Blessings Sheila Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications) Core Biopsy 2/22/02 L. Mastectomy 2/25/2002 Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg 6/2003 Reconstruction W/ Tissue Expander, Silicone Implant 9/2003 Stage IV with Mets to Supraclavicular nodes 9/2003 Began Herceptin every 3 weeks 3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes 3/2007 Added back the Xeloda with Herceptin for continued mets to nodes 5/2007 Taken Off Xeloda, no longer working 6/14/07 Taxol/Herceptin/Avastin 3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee 5/29 2008 Back on Taxol w Herceptin q 2 weeks 4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve 5/2009 Begin Rx with Navelbine/Herceptin 11/09 Progression on Navelbine Fought for and started Tykerb/Herceptin...nodes are melting!!!!! 2/2010 Back to Avastin/Herceptin 5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate Pericardial Window Surgery to Drain Pericardial Effusion 7/2010 Back to walking a mile a day...YEAH!!!! 9/2010 Nodes are back with a vengence in neck Qualified for TDM-1 EAP 10/6/10 Begin my miracle drug, TDM-1 Mixed response, shrinking internal nodes, progression skin mets after 3 treatments 12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments 2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!! 7/5/11 begin Gemzar /Herceptin for node progression 2/8/2012 Gemzar stopped, Continue Herceptin 2/20/2012 Begin Tomo Radiation to Neck Nodes 2/21/2012 I CELEBRATE 10 YEARS 5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression 6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin