HER2 Support Group Forums - View Single Post - hopeful case report--letrozole cleared up multiple brain mets

Hopeful · 05-08-2008, 08:13 AM

Geri,

You can look here for info on Tamoxifen followed by Femara: http://www.pharma.us.novartis.com/pr...e&source=01030

BTW, I recall reading that the brain is one of the largest sources of aromatase production in the body (stands to reason, there is a lot of fatty tissue). This study Lani posted may show that Femara crossed the BBB and inhibits aromatase in the brain - wouldn't that be great?

Hopeful

05-08-2008, 08:13 AM	#8
Hopeful Senior Member Join Date: Aug 2006 Posts: 3,380	Geri, You can look here for info on Tamoxifen followed by Femara: http://www.pharma.us.novartis.com/pr...e&source=01030 BTW, I recall reading that the brain is one of the largest sources of aromatase production in the body (stands to reason, there is a lot of fatty tissue). This study Lani posted may show that Femara crossed the BBB and inhibits aromatase in the brain - wouldn't that be great? Hopeful